CryoDerm Magnesium Calming Cream contains minerals that are harvested from the Dead Sea where the mineral content is at its highest containing 21 minerals. These minerals naturally occur in our bodies and are lost throughout the day, so they must be replenished. They help to treat, detoxify and cleanse our bodies. Magnesium calms nerves and muscles, aids in the reduction of cramping and hypertonicity, and combats stress and fluid retention. Calcium is also effective at increasing circulation, and strengthening bones and nails.